Nanotechnology Paves Way For Implantable Artificial Kidney

Researchers recently presented a study that could lead to the development of a surgically implantable, artificial kidney, which is built with nanotechnology. This new study could lead to the development of an alternative artificial kidney for people on dialysis, with end stage renal disease (ESRD), along with persons on waiting lists for kidney transplants.

"We aim to conduct clinical trials on an implantable, engineered organ in this decade, and we are coordinating our efforts with both the NIH and the U.S. Food and Drug Administration," Shuvo Roy, a bioengineer from UC San Francisco and lead author of the study, said in a news release.

The researchers developed a coffee cup-sized device, which works almost identically to a human kidney. The new artificial kidney has a silicon nanofilter which removes toxins, salts, small molecules and water from the blood. The device was created using semiconductor electronics and microelectromechanical systems (MEMS).

The new device functions on blood pressure and does not require electric power or pump to perform its functions.

"We are increasing the options for people with chronic kidney disease who would otherwise be forced onto dialysis," said William Fissell, a co-researcher of the study.

The artificial kidney can be connected near a patient's kidneys, which are not removed. The new kidney is connected to the patient's bladder and blood supply, and it performs the functions of a typical human kidney.

The researchers are working on making the new artificial kidney accessible to patients.

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