Physics
Nanocapsules as Infection Detectors Will Protect Burn Victims
Mark Hoffman
First Posted: Mar 26, 2013 12:29 AM EDT
Medical researchers presented a revolutionary wound dressing technology, currently in development and testing stage, which can detect infections and thus alert physicians of the infected wound by a simple color change. Infections in burn victims are hard to detect at the moment, and can be deadly.
The new method is developed especially with child burn victims in mind and could be lifesaving for young children with serious burns, in whom infections can quickly spread and end fatal, according to the researchers behind the new wound dressing.
"When a child comes back with a small burn, with a temperature, we don't know if that child has a serious infection in the burn or whether they simply have a cough or cold," said Dr. Amber Young, consultant pediatric anesthetist at Frenchay Hospital in a video posted by University of Bath. "At the moment we have purely guess work to go on."
The wound dressing employs dye-loaded nanocapsules, which are triggered by coming into contact with toxins produced by harmful bacteria. The particles then release the dye, which can been seen under ultraviolet light, indicating an infection. The system can be adapted so that it distinguishes harmful bacteria from benign bacteria normally found on the skin.
While only in prototype stages, the wound dressing's developers are excited to move forward with their system.
"We are hoping that in two to three years from now we will be able to start the first tests on healthy human volunteers," Toby Jenkins, a doctor of biophysical chemistry at University of Bath who led the design.
Currently, testing for infections required removing standard wound dressing, which be painful for burn victims and can prolong the healing process.
Also, current methods to diagnose a wound infection can take up to 48 hours, which poses a sizable problem for physicians trying to keep a patient infection free.
"However, our burns dressing gives a simple color change under UV light if a pathogenic, disease-causing bacteria is present in the burn, meaning clinicians can be alerted quickly to a potential infection," said Jenkins, according to a BBC report.
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First Posted: Mar 26, 2013 12:29 AM EDT
Medical researchers presented a revolutionary wound dressing technology, currently in development and testing stage, which can detect infections and thus alert physicians of the infected wound by a simple color change. Infections in burn victims are hard to detect at the moment, and can be deadly.
The new method is developed especially with child burn victims in mind and could be lifesaving for young children with serious burns, in whom infections can quickly spread and end fatal, according to the researchers behind the new wound dressing.
"When a child comes back with a small burn, with a temperature, we don't know if that child has a serious infection in the burn or whether they simply have a cough or cold," said Dr. Amber Young, consultant pediatric anesthetist at Frenchay Hospital in a video posted by University of Bath. "At the moment we have purely guess work to go on."
The wound dressing employs dye-loaded nanocapsules, which are triggered by coming into contact with toxins produced by harmful bacteria. The particles then release the dye, which can been seen under ultraviolet light, indicating an infection. The system can be adapted so that it distinguishes harmful bacteria from benign bacteria normally found on the skin.
While only in prototype stages, the wound dressing's developers are excited to move forward with their system.
"We are hoping that in two to three years from now we will be able to start the first tests on healthy human volunteers," Toby Jenkins, a doctor of biophysical chemistry at University of Bath who led the design.
Currently, testing for infections required removing standard wound dressing, which be painful for burn victims and can prolong the healing process.
Also, current methods to diagnose a wound infection can take up to 48 hours, which poses a sizable problem for physicians trying to keep a patient infection free.
"However, our burns dressing gives a simple color change under UV light if a pathogenic, disease-causing bacteria is present in the burn, meaning clinicians can be alerted quickly to a potential infection," said Jenkins, according to a BBC report.
See Now: NASA's Juno Spacecraft's Rendezvous With Jupiter's Mammoth Cyclone