A Colorful Image That Could Lead to Better Antibiotics
It may look like a tangle of colorful, squiggly lines, but it’s actually a sophisticated molecular machine called a ribosome. A ribosome’s job is to build and assemble proteins, the workhorse compounds that sustain all living things. The image is also a milestone: It’s the first time an atom-by-atom structure of a ribosome has been seen attached to a molecule that controls its motion.
That’s big news if you’re a structural biologist – but there’s another way to look at this image, one that anyone who has suffered a bacterial infection can appreciate. The image is also a roadmap to better treatments, as this particular ribosome is from a bacterium.
Ultimately, better understanding of bacterial ribosomes will help scientists come up with better ways to interfere with them. Now, with an atomic-scale structure in hand, studying the chemical and molecular forces involved is possible. -- by Amber Harmon, © i SGTW
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